Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus (PRRSV), is globally the most economically important disease in commercial pigs, and novel control strategies are sought. This paper explores the potential to use host genetics to decrease the impact of PRRS on reproductive sows. The conclusions of this research is that there are within-breed genetic variation for commercially relevant traits that could be expoited in future breeding programs against PRRSV infection. Selection for PRRS resistance would be desirable to the industry because effective control measures remain elusive.

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