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Prairie Swine Centre is grateful for the assistance of the George Morris Centre in developing the economics portion of Pork Insight.

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Title:
Clostridium perfringens beta-toxin targets endothelial cells in necrotizing enteritis in piglets
Author(s): J. Miclard, M. Jäggi, E. Sutter, M. Wyder, B. Grabscheid, H. Posthaus
Publication Date: January 1, 2009
Reference: Veterinary Microbiology 137 (2009) 320–325
Country: Switzerland

Summary:

To investigate localization of CPB in naturally occurring necrotizing enteritis, we evaluated 52 piglets with spontaneously acquired C. perfringens type C enteritis and 14 control animals by immunohistochemistry. It was concluded that the pathogenesis of C. perfringens type C induced necrotizing enteritis involves binding of CPB to endothelial cells in the small intestine during the early phase of the disease.

For more information the full article can be found at http://www.sciencedirect.com/science/journal/03781135

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