Age and growth factors in porcine full-thickness wound healing

Posted in: Welfare by admin on January 1, 2001 | No Comments

It has been recognized that the rate of cutaneous wound healing declines with age, yet the molecular processes that affect this decline remain poorly understood. The purpose of this study was to compare reepithelaization and contraction rates, and growth factor profiles in full-thickness wounds in swine of various ages. Multiple full-thickness excisional wounds were created on the dorsum of 24-month-old (n=2), 4-month-old (n=2)Yucatan Minigigs. The extent of reepitheliatization was shown to decrease with increasing age in a manner that was statistically significant among the 2-month-old (79%), 4-month-old (48%), and 24-month-old pigs (22%). Enzyme-linked immunosorbent assay results showed that endogenous vascular endothelial growth factor concetrations in the 2 and 4 month old animals pecked on day 4, reaching levels of 482 pg/ml and 420 pg/.ml, respectively. In the 24-month-old pigs the vascular endothelial growth factor levels in the older pigs reached only 120 pg/ml, representing a four-fold decrease in concentration compared to the younger pigs. A comparison of platelet-derived growth factor-BB concentrations across the age groups showed similar patterns in the 2 and 4 month old pigs (peaks of 77 and 91 pg/ml on days 2 and 3, respectively), and levels in the 24-month-old were below the sensitivity level (31.5 pg/ml) of the assay. Transforming growth factor-b1 levels across the age groups did not differ in a manner that was stratistically significant, and all age groups peaked on day 9. Wound contaction showed no statistical differences among the age groups from days 3 to 9. On day 11, however, wound contraction in 2-month-old pigs was about 10% fraster than in 24-month-old pigs (p<0.05). These data suggest a possible new algorithm for treating wounds in aged skin, by which exogenous growth factors can be added to the wound microenvironment in doesse and at times that match the growth factor profiles observed in wounds made in younger skin.

AN INTELLIGENT ALARM FOR EARLY DETECTION OF SWINE EPIDEMICS BASED ON NEURAL NETWORKS

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Dietary lupins (Lupinus angustifolius and Lupinus albus) can increase digesta retention in the gastrointestinal tract of pigs

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La sA

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Les agriculteurs d’aujourd’hui font partie de l’industrie de la production alimentaire et ils sont fiers de produire des aliments sains de haute qualitA

Public Involvement in the Siting of Large Scale Hog Facilities: Lessons for Pork Producers from Four Alberta Communities

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The recent increases in intesnive hog production in Alberta, Saskatchewan, and Manitoba has corresponded to increased hostility and legal challenges within rual agrcultural communities over the siting of intenive facilties. Long expensive appeals to siting decisions suggest the need for public involvement in intensive livestock management. A 1998 study prepared an assessment of the socio-economic impact of hogs in Alberta. Their conclusions, recommended that pork producers strike a balance between the science-based aspecs of their plan and good neighbor policies, inclusing communication with surrounding neighbours, public awareness and solid environmental planning. Our research focuses on the public involvment in the siting of intesnive hog developments in Alberta, the rteasons for conflict, and the ways to minimize conflict through constructive public particiapation methods

Understanding the Soil-Lanscape: Implications for Managing Manure

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Introduction
Application of livestock manure to land has been conducted for centuries to increase agricultural productivity by providing nutrients and organic materials that improve overall soil tilth and fertility. Manure is a valuable source of crop nutrients and organic matter provided that it is used as a nutrient amendment based on sound agronomic principles. Soil and water quality deterioration following manure addition may occur when agronomic principles are not adhered to or when manure is simply disposed of as a waste on agricultural land. It is important for the land manager to understand the pros and cons of manure application to land as well as understand the limitations of the land base to which the manure is applied. One of the factors that influences the fate of manure applied to land is the variability of the soillandscape. Unfortunately, the variability of soils within a given landscape is generally not well appreciated and manure (or fertilizers) is applied uniformly across a given field with little consideration given to the variability in soil and hydrologic processes within the field. This paper presents the concept of the soil-landscape and describes how an understanding of this concept is important for managing manure on agricultural land. What is the a

Dust and Bioaersol Concentrations in Two Swin Finishing Buildings in Kanas

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Air quality was assessed in 2 commercial swine finishing barns, one naturally ventilated and the other mechanically ventilated. The concentrations of inhalable dust IDC) and respirable dust (RDC), bioaerosols, carbon dioxide, and ammonia as well as particle size distribution, air temperature, relative humidity inside the barns were measured for 41 consecutive weeks covering three batches of pigs in each barn. The mean IDC, RDC, total viable particles, and respirable particles in the naturally ventilated barn were 2.19 mg/m3, 0.10 mg/m3, 6.0 x 1^4 and 9.8 x 10^3 respectively. The two barns did not differ significantly in any of the above parameters or in particle size distribution. The IDC and RDC inside the two barns correlated significantly with the weight of the pigs. The IDC also correlated with the outside air temperature, and the RDC correlated with the temperature difference between the outside and inside air. Significant but small correlation was found between the total forming units inside the barns and the weight of the pigs.

Availability of Nitrogen in Solid Manure Amendments with Different C:N Ratios

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MEASUREMENT OF LEAKAGE FROM EARTHEN MANURE STRUCTURES IN IOWA

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Pulmonary diseases caused by airborne contaminants in swine confinement buildings

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