This study evaluated the ability of a live attenuated E. rhusiopathiae strain to become persistently established in pigs after intranasal exposure and its potential to cause clinical signs consistent with swine erysipelas after being administered directly into the nasopharynx of healthy pigs. It was found that the live attenuated E. rhusiopathiae strain would unlikely revert to a virulat state when used in a field setting.

For more information the full article can be found at http://www.sciencedirect.com/science/journal/03781135