This topic reviews the process used to gather, screen for relevance, and assess the quality of current literature regarding published methods of swine euthanasia as well as the summary of the results of the data analysis, including a description of the welfare measures included in papers describing euthanasia. More than 4,500 citations have been collected using terms for “euthanasia,” “slaughter methods,” and “swine”; preliminary screening removed articles that were either not relevant to the topic of swine or euthanasia/slaughter methods or not in English. The second level of screening segregates primary research articles from editorials/opinions, surveys, or other narrative reviews. Only primary research is used for the final quality assessment review and analysis, but review papers are used to check the thoroughness of the reference list. The final set of literature evaluates and compares measurements of pain and aversion, the achievement of death, and other physiologic parameters described in the euthanasia paper. The intent of this research is to provide this scientific body of literature to swine veterinarians and the swine industry as well as identify areas of opportunity where more research is needed. Further, the intent is to highlight areas where reporting is deficient or incomplete and improve the quality of reporting of papers describing euthanasia.