European-like Type 1 porcine reproductive and respiratory syndrome virus (PRRSV) isolates, known
\nas North American (NA) Type 1 PRRSV, appeared in United States (U.S.) swine herds in 1999. Their
\ndiversity and evolution were studied over a fiveyear period by constructing phylogenetic trees using
\nnsp2 and ORF5 sequences of 20 NAType 1 isolates, including the only known isolate from Hawaii. All
\nbut two of the isolates possessed the same 51-nt deletion in nsp2, suggesting a clonal origin. Parsimony and distance analysis showed that viruses could be placed into two distinct sub-clades, which were similar for both nsp2 and ORF5. An incongruity between the two trees identified one isolate, 04-41, as the product of recombination. Recombination analysis using SimPlot identified a break point located downstream of the nsp2=3 junction. Results from this study suggest that NAType 1 PRRSVin the U.S. is a well-established and rapidly evolving group. However, the forces driving genetic diversity and separation are complex and remain to be elucidated.<\/p>\n","protected":false},"excerpt":{"rendered":"
European-like Type 1 porcine reproductive and respiratory syndrome virus (PRRSV) isolates, known as North American (NA) Type 1 PRRSV, appeared in United States (U.S.) swine herds in 1999. Their diversity and evolution were studied over a fiveyear period by constructing phylogenetic trees using nsp2 and ORF5 sequences of 20 NAType 1 isolates, including the only […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[930],"tags":[14125,8882,8428,2854,2817,8547,6013,13175,12670,6226,3804,111,6227,10859,5249,3465,16262,19940,6228,17743,4181,5303,35,20911,4874,8429,23461],"class_list":["post-3985","post","type-post","status-publish","format-standard","hentry","category-production","tag-2007-diversity-and-evolution-of-a-newly-emerged-north-american-type-1-porcine-arterivirus-analysis-of-isolates-collected-between-1999-and-2004-arch-virol-15210091017","tag-al","tag-artervirus","tag-bin","tag-cla","tag-complex","tag-diversity","tag-diversity-and-evolution-of-a-newly-emerged-north-american-type-1-porcine-arterivirus-analysis-of-isolates-collected-between-1999-and-2004","tag-down","tag-evolution","tag-genetic","tag-health","tag-isolates","tag-nat","tag-north-america","tag-pea","tag-pl","tag-porc","tag-porcine-artervirus","tag-prod","tag-prrs","tag-prrsv","tag-swine","tag-t","tag-tan","tag-viruses-artervirus","tag-23461"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/3985","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=3985"}],"version-history":[{"count":0,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/3985\/revisions"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=3985"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=3985"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=3985"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}