The objective of the current study was
\nto investigate whether plasma citrulline or intestinal
\nfatty acid-binding protein (I-FABP) concentrations
\nmight be used as longitudinal markers for small intestinal
\nfunction in piglets after weaning. Plasma citrulline
\nand I-FABP concentrations were measured longitudinally
\nin weaned and unweaned piglets, and related to
\nintestinal absorption values (i.e., plasma mannitol and
\nd-xylose concentrations in a sugar absorption test).
\nWithin each litter (n = 10), 2 piglets with a close-tolitter-
\naverage BW were selected. At 20.8 \u00b1 0.4 d of age,
\nthe selected piglets per litter were either weaned conventionally
\n(CW) or remained with the sow (UNW).
\nOne day before, and 0.5, 2, 4, and 7 d after weaning
\nof the CW piglets, the selected piglets of both groups
\nwere subjected to a sugar absorption test. After a 2-h
\nfast, piglets were administered an oral dose of 2 mL\/
\nkg of sugar solution, containing 50 mg\/kg of mannitol
\nand 100 mg\/kg of d-xylose. One hour after administration,
\na blood sample was collected from a jugular vein
\nfor determination of plasma I-FABP, citrulline, mannitol,
\nand d-xylose concentrations. Plasma I-FABP concentration
\nshowed great variation within treatments,
\nand no difference was observed in plasma I-FABP concentrations
\nbetween the CW and UNW treatments (P
\n= 0.63). The absorption of d-xylose was not different
\nbetween treatments (P = 0.83). Mannitol absorption,
\nhowever, was less in the weaned CW piglets compared
\nwith the UNW piglets (P = 0.003), with the nadir on d
\n4 postweaning. Weaning also reduced plasma citrulline
\nconcentrations in the CW treatment compared with the
\nUNW treatment (P < 0.001). On d 4 and 7 postweaning,\nplasma citrulline concentrations of CW piglets\nwere less (P < 0.001 and P = 0.0013) than preweaning\nvalues. Furthermore, in the CW treatment, plasma\ncitrulline concentrations correlated with plasma mannitol\nconcentrations at d 4 postweaning (r = 0.89, P\n= 0.008) and overall (r = 0.76, P = 0.001). Based on\nthese results, plasma citrulline concentration seems to\nbe a possible marker for monitoring intestinal function\nin pigs after weaning.\n<\/p>\n","protected":false},"excerpt":{"rendered":"
The objective of the current study was to investigate whether plasma citrulline or intestinal fatty acid-binding protein (I-FABP) concentrations might be used as longitudinal markers for small intestinal function in piglets after weaning. Plasma citrulline and I-FABP concentrations were measured longitudinally in weaned and unweaned piglets, and related to intestinal absorption values (i.e., plasma mannitol […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[930],"tags":[1809,8882,2854,6776,6777,16845,23694,22809,2851,20007,6778,818,10858,8306,10859,14,126,89,33,16262,92,104,6779,20911,1579,52,1055,3790,6244,15383,3325,77],"class_list":["post-4069","post","type-post","status-publish","format-standard","hentry","category-production","tag-acid","tag-al","tag-bin","tag-biological-marker","tag-citrulline","tag-close","tag-dir","tag-fast","tag-fat","tag-gh","tag-intestinal-fatty-acid-binding-protein","tag-litter","tag-mark","tag-markers","tag-nat","tag-pig","tag-piglet","tag-piglets","tag-pigs","tag-pl","tag-plasma","tag-sow","tag-sugar-absorption","tag-t","tag-test","tag-treatment","tag-variation","tag-weaned","tag-weaned-pig","tag-weaned-piglet","tag-weaned-piglets","tag-weaning"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/4069","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=4069"}],"version-history":[{"count":0,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/4069\/revisions"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=4069"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=4069"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=4069"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}