Vaccines traditionally consist of either attenuated (weakened) live, or inactivated (killed) pathogens. In general, live vaccines are more effective as they tend to stimulate stronger immune responses, similar to natural infection. However, live vaccines have the risk of potentially causing disease, especially in animals that are compromised by stress or other diseases. Killed vaccines are very safe but often induce weaker immune responses and require the addition of vaccine adjuvants. Live vectored vaccines or DNA vaccines are recently-developed vaccine technologies that are very safe and capable of inducing immune responses that are similar to natural infection. However, neither DNA vaccines nor vectored vaccines are licensed for pigs in Canada, though promising experimental vaccines are already in the final stages of development. At the Vaccine and Infectious Disease Organization (VIDO), several projects are aimed at developing novel and more effective vaccines for pigs. Infectious diseases remain the major cause of morbidity and mortality in swine production. Recent outbreaks of porcine circovirus (PCV), porcine reproductive respiratory syncytial virus (PRRSV) or swine influenza virus (SIV) have demonstrated that infectious diseases can have devastating effects on Canada\u2019s swine industry. Vaccination represents a very cost-effective strategy to reduce animal suffering, improve the economics of livestock production, and reduce the spread of many infectious diseases from animals to humans. The importance of modern vaccine research is highlighted by the need for better food safety and the threat of importing devastating diseases such as foot-and-mouth disease or hog cholera.<\/p>\n","protected":false},"excerpt":{"rendered":"
Vaccines traditionally consist of either attenuated (weakened) live, or inactivated (killed) pathogens. In general, live vaccines are more effective as they tend to stimulate stronger immune responses, similar to natural infection. However, live vaccines have the risk of potentially causing disease, especially in animals that are compromised by stress or other diseases. Killed vaccines are […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[930],"tags":[6265,8882,640,10033,6784,190,846,19644,60,5845,3734,286,20007,34,6577,3794,2345,26380,2679,572,13370,5381,606,10859,967,7816,15459,14,33,19940,6230,17743,27282,13636,4181,5303,1240,2365,396,14980,110,35,16004,1131,20911,4874,6053,1304,4384],"class_list":["post-4136","post","type-post","status-publish","format-standard","hentry","category-production","tag-adjuvants","tag-al","tag-animal","tag-arc","tag-cos","tag-cost","tag-cost-effective","tag-dd","tag-disease","tag-diseases","tag-dna","tag-dust","tag-gh","tag-hog","tag-immune","tag-immune-response","tag-improvement","tag-infec","tag-infection","tag-injection","tag-ken","tag-light","tag-mortality","tag-nat","tag-pathogens","tag-pcv","tag-ped","tag-pig","tag-pigs","tag-porc","tag-porcine-circovirus","tag-prod","tag-production","tag-project","tag-prrs","tag-prrsv","tag-research","tag-risk","tag-safety","tag-search","tag-stress","tag-swine","tag-swine-industry","tag-swine-production","tag-t","tag-tan","tag-use","tag-vaccine","tag-vido"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/4136","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=4136"}],"version-history":[{"count":0,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/4136\/revisions"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=4136"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=4136"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=4136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}