The porcine corticotropin-releasing hormone (CRH) gene is a functional\u2013positional candidate
\nfor quantitative tract loci on porcine chromosome 4 with major effects on growth and
\ncarcass composition. In addition, the central role of CRH in the neuroendocrine response to
\nstress implicates the CRH gene as a functional candidate for meat quality. Association of a
\nsingle nucleotide polymorphism (SNP) in the promoter region of the porcine CRH gene
\n(g.233C>T) with several growth, carcass and meat quality traits was examined using more
\nthan 2000 individuals from four commercial lines: German Landrace (LR), Pietrain (Pi),
\nGerman Large White \u00b7 German Landrace (F1) and the German commercial fattening pig
\ncross of Pietrain \u00b7 F1 (PiF1). Significant association of the CRH SNP was found with feed
\nconversion ratio in the PiF1 line, with carcass length in the LR line and with lean content in
\nthe F1, LR and Pi lines. Moreover, significant association with meat colour was found in the
\nPi and LR lines; however, the effects were in opposite directions. The presented results
\nindicate that sequence variation in the porcine CRH gene has no major effect on growth and
\ncarcass composition in commercial pig lines, although it may significantly contribute to
\nvariation in meat quality. The g.233C>T SNP may be in incomplete linkage disequilibrium
\nwith causal mutations and\/or exhibit effects in the context of DNA variation at other
\ninteracting loci.<\/p>\n","protected":false},"excerpt":{"rendered":"
The porcine corticotropin-releasing hormone (CRH) gene is a functional\u2013positional candidate for quantitative tract loci on porcine chromosome 4 with major effects on growth and carcass composition. In addition, the central role of CRH in the neuroendocrine response to stress implicates the CRH gene as a functional candidate for meat quality. Association of a single nucleotide […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2102],"tags":[8882,10033,13816,5692,3965,2235,5742,19644,23694,11517,3734,2851,7904,6904,46,20007,158,7099,11443,13330,94,27284,63,2560,14,16262,19940,95,5743,20132,20912,110,20911,26223,24994,1055],"class_list":["post-4807","post","type-post","status-publish","format-standard","hentry","category-meat-quality","tag-al","tag-arc","tag-ass","tag-carcass-traits","tag-content","tag-conversion","tag-corticotropin-releasing-hormone","tag-dd","tag-dir","tag-directions","tag-dna","tag-fat","tag-fattening","tag-fee","tag-feed","tag-gh","tag-growth","tag-landrace","tag-lean-content","tag-lou","tag-meat","tag-meat-quality","tag-performance","tag-pietrain","tag-pig","tag-pl","tag-porc","tag-quality","tag-single-nucleotide-polymorphism","tag-snp","tag-some","tag-stress","tag-t","tag-the-effects","tag-usa","tag-variation"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/4807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=4807"}],"version-history":[{"count":0,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/4807\/revisions"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=4807"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=4807"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=4807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}