A genetically modified animal (transgenic) is one whose genome contains DNA of exogenous origin that has been introduced through experimental manipulation. Although there is a growing concern about health and welfare of the animals involve in trasgenesis research, few studies have been conducted to evaluate the welfare of transgenic farm animals. In this paper the authors discuss (potential) welfare problems in farm animals associated with transgenic technologies, and they are examining the strategy of studying health and welfare of transgenic farm animals. There is evidence showing that treatments imposed in the context of farm animal transgenesis are by no means biologically neutral and may compromise animal health and welfare. Factors posing a risk for the welfare of transgenic farm animals include integration of a transgene within an endogenous gene with possible loss of host gene function (insertional mutations) and in vitro reproductive technologies employed in the process of generating transgenic farm animals that may results in an increased incidence of difficult parturition and fetal and neonatal losses and the development of unusually large or otherwise abnormal offspring. Critical components of a scheme for evaluating welfare of transgenic farm animals are identified and concrete steps with regard to breeding and testing of transgenic farm animals are presented in this paper. It is anticipated that systematic research into the welfare of farm animals involved in transgenesis will facilitate the use of the safest experimental protocols as well as the selection and propagation of the healthiest animals and, thereby, enable technological progress that could be ethically justified.<\/p>\n","protected":false},"excerpt":{"rendered":"
A genetically modified animal (transgenic) is one whose genome contains DNA of exogenous origin that has been introduced through experimental manipulation. Although there is a growing concern about health and welfare of the animals involve in trasgenesis research, few studies have been conducted to evaluate the welfare of transgenic farm animals. In this paper the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[928],"tags":[8882,640,2993,70,10033,13816,19216,24226,49,2349,2344,3734,3804,20007,111,14122,3005,10859,16262,17743,2365,14980,23609,11941,20911,1579,14923,14909,19911,52,6053,27281],"class_list":["post-5119","post","type-post","status-publish","format-standard","hentry","category-welfare","tag-al","tag-animal","tag-animal-healthanimal-welfarefarm-animal-welfarefarm-animalsfarminghealthrisk-assessmenttransgenictransgenic-animalswelfare","tag-animal-welfare","tag-arc","tag-ass","tag-assess","tag-assessing-the-welfare-of-transgenic-farm-animals","tag-assessment","tag-breed","tag-breeding","tag-dna","tag-genetic","tag-gh","tag-health","tag-health-and-welfare-of-transgenic-farm-animals","tag-host","tag-nat","tag-pl","tag-prod","tag-risk","tag-search","tag-spring","tag-systematic","tag-t","tag-test","tag-the-welfare","tag-the-welfare-of","tag-transgenesis-may-affect-farm-animal-welfare-a-case-for-systematic-risk-assessment","tag-treatment","tag-use","tag-welfare"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/5119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=5119"}],"version-history":[{"count":0,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/5119\/revisions"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=5119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=5119"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=5119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}