Amino acid metabolism by the splanchnic tissues, which include the liver and
\nthe portal-drained viscera (PDV), determines amino acid availability for protein
\ndeposition in peripheral tissues and thus whole-body growth. Threonine, lysine
\nand methionine are the first limiting amino acids in milk-based and cereal diets
\nof growing pigs. Studies have shown that both dietary essential and nonessential
\namino acids are extensively utilized by intestinal tissues for the
\ngeneration of energy, protein synthesis, and other biosynthetic purposes.
\nThreonine, with 60-80% extraction in first-pass of the dietary intake, is the
\nsingle most utilized essential amino acid by the PDV. This can most likely be
\nattributed to the incorporation of threonine into membrane-associated and
\nsecretory mucosal glycoproteins, the so-called mucins, which are an important
\ncomponent of the protective mucus covering the gut epithelium. In pigs, mucin
\nrepresents 11% of the basal endogenous ileal losses of protein with threonine
\ncontributing approximately 30% to the total amino acid content. Thus, the
\nsecretion, recycling, and loss of intestinal mucins have a substantial impact on
\nthe maintenance requirement for threonine. Factors that increase the
\nproduction of mucin will increase threonine requirements and consequently,
\ndecrease the availability of threonine and energy for growth and production.
\nFurthermore, the availability of threonine may limit intestinal mucin synthesis
\nand therefore reduce gut barrier function. This highlights the importance of
\nthreonine for maintaining intestinal integrity, which is essential for regulating
\ndietary amino acid supply for the whole body<\/p>\n","protected":false},"excerpt":{"rendered":"
Amino acid metabolism by the splanchnic tissues, which include the liver and the portal-drained viscera (PDV), determines amino acid availability for protein deposition in peripheral tissues and thus whole-body growth. Threonine, lysine and methionine are the first limiting amino acids in milk-based and cereal diets of growing pigs. Studies have shown that both dietary essential […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[928],"tags":[1809,8882,580,13816,3965,231,577,1287,27278,20007,651,517,158,5381,848,1290,7258,14784,79,14,33,16262,17743,27282,20911,4874,1579,1467,18011],"class_list":["post-5464","post","type-post","status-publish","format-standard","hentry","category-welfare","tag-acid","tag-al","tag-amino-acids","tag-ass","tag-content","tag-cover","tag-diet","tag-diets","tag-energy","tag-gh","tag-growing-pig","tag-growing-pigs","tag-growth","tag-light","tag-lysine","tag-methionine","tag-milk","tag-ness","tag-nutrition","tag-pig","tag-pigs","tag-pl","tag-prod","tag-production","tag-t","tag-tan","tag-test","tag-threonine","tag-tot"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/5464","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=5464"}],"version-history":[{"count":0,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/5464\/revisions"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=5464"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=5464"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=5464"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}