{"id":8651,"date":"2011-08-11T14:46:29","date_gmt":"2011-08-11T14:46:29","guid":{"rendered":"http:\/\/prairieswine.com\/rsc\/?p=8651"},"modified":"2012-07-06T16:02:47","modified_gmt":"2012-07-06T22:02:47","slug":"effects-of-chronic-exposure-of-diets-with-reduced-concentrations-of-aflatoxin-and-deoxynivalenol-on-growth-and-immune-status-of-pigs","status":"publish","type":"post","link":"http:\/\/prairieswine.com\/rsc\/effects-of-chronic-exposure-of-diets-with-reduced-concentrations-of-aflatoxin-and-deoxynivalenol-on-growth-and-immune-status-of-pigs\/","title":{"rendered":"Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs"},"content":{"rendered":"

This study investigated the growth and immune responses of pigs fed diets containing reduced concentrations of aflatoxin (AF) and deoxynivalenol (DON) from naturally contaminated corn. Sixty gilts (13.9 kg of BW) were randomly assigned to 4 treatments (5 replicate pens per treatment and 3 pigs per pen): A (a control diet without detectable AF and DON); B (a diet with 60 \u03bcg of AF\/kg and 300 \u03bcg of DON\/kg); C (a diet with 120 \u03bcg of AF\/kg and 600 \u03bcg of DON\/kg); and D (a diet with 180 \u03bcg of AF\/kg and 900 \u03bcg of DON\/kg). Pigs were allowed ad libitum access to feed and water for 33 d. Feed intake and BW were measured weekly and pigs were bled (8 mL) on d 33 to measure the numbers of blood cells, to conduct liver function tests, and to measure immunological variables including IgG, IgM, interferon \u03b3, IL4, IL6, and tumor necrosis factor \u03b1. One pig representing the average BW of each pen was killed to obtain the liver, kidneys, and spleen for weight, tissue color measurement, and histological evaluation of tissue damage. When compared with A, pigs in C and D tended to have reduced ADG (0.52 vs. 0.43 and 0.41 kg\/d, respectively) and ADFI (1.04 vs. 0.92 and 0.88 kg\/d, respectively). White blood cell count of pigs in D (23.4 cells\/\u03bcL) was greater than those in A, B, and C (18.4, 18.5, and 16.8 cells\/\u03bcL, respectively. Serum tumor necrosis factor \u03b1 concentration of pigs in D (335 pg\/mL) differed from those in A and C (299 and 290 pg\/mL, respectively). Pigs in B and D had greater fibrosis in liver tissues than those in A. Collectively, this study shows that diets containing both AF and DON greater than 60 and 300 \u03bcg\/kg, respectively, may reduce growth and decrease feed intake, whereas diets containing 120 \u03bcg of AF\/kg and 600 \u03bcg of DON\/kg may result in altered immune health, systemic inflammation, and partial liver damage, causing further reduction in growth of pigs.<\/span><\/span><\/span><\/p>\n

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To view this complete article please visit: http:\/\/jas.fass.org\/<\/a><\/p>\n

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This study investigated the growth and immune responses of pigs fed diets containing reduced concentrations of aflatoxin (AF) and deoxynivalenol (DON) from naturally contaminated corn. Sixty gilts (13.9 kg of BW) were randomly assigned to 4 treatments (5 replicate pens per treatment and 3 pigs per pen): A (a control diet without detectable AF and […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[930],"tags":[4685,7937,8882,13816,2817,6988,5215,577,1287,4663,13872,10280,6904,46,925,20007,105,3322,158,111,15065,6577,3794,5851,9846,10859,14,33,15530,16262,10091,14805,1533,35,20911,26635,1579,52,12043,69,1301],"class_list":["post-8651","post","type-post","status-publish","format-standard","hentry","category-production","tag-access","tag-aflatoxin","tag-al","tag-ass","tag-cla","tag-color","tag-deoxynivalenol","tag-diet","tag-diets","tag-don","tag-effect-deoxynivalenol-in-pig","tag-effects-of-chronic-exposure-of-diets-with-reduced-concentrations-of-aflatoxin-and-deoxynivalenol-on-growth-and-immune-status-of-pigs","tag-fee","tag-feed","tag-feed-intake","tag-gh","tag-gilt","tag-gilts","tag-growth","tag-health","tag-histopathological-study-of-liver-aflatoxin","tag-immune","tag-immune-response","tag-immune-system","tag-lee","tag-nat","tag-pig","tag-pigs","tag-pigs-per-pen","tag-pl","tag-porcine-stress-syndrome","tag-rn","tag-size","tag-swine","tag-t","tag-temi","tag-test","tag-treatment","tag-tumor-necrosis-factor-concentration-swine","tag-water","tag-weight"],"_links":{"self":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/8651","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=8651"}],"version-history":[{"count":6,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/8651\/revisions"}],"predecessor-version":[{"id":8654,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/8651\/revisions\/8654"}],"wp:attachment":[{"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=8651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=8651"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=8651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}