The inherent food safety of a novel gonadotropin-releasing factor (GnRF) vaccine,intended to be administered by injection to male pigs for the control of boar taint, was confirmed using several animal models. In addition to conventional oral bioavailability studies, an experiment was also performed to check for the presence of a direct hormonal effect of the vaccine antigen. It was confirmed that there is no risk to human health from the consumption of pork from pigs administered this boar taint vaccine.