It was hypothezied that that a monoclonal antibody (McAb) could display cytotoxicity only to the adipocytes from subcutaneous and abdominal adipose tissues and produce a suppressive effect to these fat cells and tissues, but would not produce side-effect to other tissues. In this study the effects of this McAb on the growth performance, carcass composition, fat metabolism and adipocyte tissue development was investigated to explore the possible mechanism of McAb to restrain the fat deposition and improve the carcass composition. The study did find that this McAb could improve the carcass composition by reducing fat percentage which was regulated by increasing fat mobilization and suppressing the fat deposition in adipose tissue.
For more information the full article can be found at http://www.journals.elsevierhealth.com/periodicals/livsci
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