A study was conducted to evaluate the dietary effect of adding increasing concentrations of distillers dried grains with solubles (DDGS) to cornand soybean meal-based sow lactation diets on sow and litter performance, energy and N digestibility, plasma urea N (PUN), and milk fat and protein concentrations. Mixed-parity sows [n = 307; 221 kg of BW, 4.54 parities, litter size of 10.6, and litter weight at birth (alive) of 15.14 kg] were assigned randomly to 1 of 5 dietary treatments: control (CON; corn-soybean meal); 10, 20, and 30% DDGS; and 30% DDGS high-protein (HP) diets. Sows were moved to farrowing rooms on d 109 of gestation and were fed the dietary treatments until weaning. Within each treatment group, feces and urine for energy and N digestibility analysis (from d 10 to 12 of lactation) and blood for PUN analysis and milk fat and protein concentrations (on d 0 and 19 of lactation) were collected from 6 randomly chosen parity 3 to 5 sows. There were no dietary effects of DDGS on ADFI of sows and sow backfat change. However, sows fed 30% DDGS HP lost more BW compared with sows fed CON. There were no dietary effects of DDGS on preweaning mortality of piglets, litter weight gain, and piglet ADG. Dietary treatments did not affect DE, ME, N retention, or N digestibility of the diets. There were no differences in the concentrations of fat and protein in milk at weaning (d 19) among dietary treatments. Sows fed 20 and 30% DDGS had less PUN at weaning (d 19) than sows fed CON and 30% DDGS HP. Inclusion of up to 30% DDGS in a lactation diet did not affect sow and litter performance, DE and ME contents of the diets, N retention and digestibility, and milk composition compared with sows fed a cornsoybean meal CON diet. It was concluded that addition of up to 30% DDGS in a lactation diet will support satisfactory sow and litter performance.

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