Nursery pig diets should be chosen to adjust pigs quickly to a cheaper and simpler diet, maximize feed intake, and be highly digestible. After weaning the pig’s digestive tract undergoes an acute phase and then an adaptive phase. Pigs have high turnover of portal-drained viscera tissue, which requires large amounts of protein turnover and energy. Diets can be formulated to support the turnover in weanling pigs. Antibiotic use has been coming under increasing pressure, so alternatives to help nursery growth can be considered. Probiotic benefit is debatable as there is a large variation in strain and amount used, herd health status, and amount consumed in the nursery. However, feeding the sow probiotics during lactation may be able to benefit the pigs pre- and post-weaning. Liquid feeding may also be easier on post-weaning digestive tracts. Insoluble dietary fibre can reduce diarrhea, although it may be more useful in areas where antibiotics are already banned. Pro-inflammatory cytokines can lead to an immune response, and fatty acids have been shown to reduce the inflammatory response. Feed quality, particle size, and pelleting are also considerations when choosing a nursery diet.