{"id":14938,"date":"2011-08-13T13:02:10","date_gmt":"2011-08-13T19:02:10","guid":{"rendered":"http:\/\/prairieswine.com\/rsc\/?p=14938"},"modified":"2013-08-13T13:06:21","modified_gmt":"2013-08-13T19:06:21","slug":"the-first-limiting-amino-acid-in-late-gestation-may-not-be-lysine","status":"publish","type":"post","link":"https:\/\/prairieswine.com\/rsc\/the-first-limiting-amino-acid-in-late-gestation-may-not-be-lysine\/","title":{"rendered":"The First Limiting Amino Acid in Late Gestation may not be Lysine"},"content":{"rendered":"<p>The order of first limiting AA in late gestation was determined in 14\u00a0sows (6 gilts, 8 2nd parity sows) using the AA deletion technique. A positive\u00a0control (PC) diet was formulated to contain all essential AA at 160% of current\u00a0recommendations (NRC 1998). Lysine, threonine, tryptophan and branchedchain\u00a0AA were each removed from the PC diet to 60% of current\u00a0recommendations (PC-Lys, PC-Thr, PC-Trp, PC-BCAA, respectively). Sows\u00a0received each of the diets in random order. Plasma urea nitrogen, indicator\u00a0AA oxidation and protein turnover (L[1-13C]phenylalanine as tracer AA) were\u00a0used to evaluate the response to dietary AA deletion from 90-111 d of\u00a0gestation. Data was analyzed using a Mixed model with sow as random\u00a0variable. Parity was tested as a covariate but was not significant. Fasted\u00a0plasma urea nitrogen (mg\/dL) was highest (P &lt; 0.09) for the PC-Lys (11.77)\u00a0diet compared to the PC (8.89) diet followed by the PC-BCAA (10.81) and PCTrp\u00a0(10.74) diets. Indicator AA oxidation (%) tended to be higher (P &lt; 0.15) for the PC-Thr (18.8) and PC-Trp (18.4) diets compared to the PC (16.4) diet.\u00a0Tracer flux and protein breakdown (\u03bcmol\/kg body wt per h, P &lt; 0.05) were\u00a0higher on the PC-Trp (91.57 and 45.08, respectively) diet compared to the PC\u00a0(73.72 and 27.97, respectively) diet. The first limiting AA in late gestation may\u00a0be Thr or Trp rather than Lys but appears to be dependent on the response\u00a0parameter.\u00a0Changes in the order of first limiting AA in late gestation in sows\u00a0means that the traditional Lys to AA ratio used in diet formulations, based on\u00a0growing pig data, may not apply to pregnant sows.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The order of first limiting AA in late gestation was determined in 14\u00a0sows (6 gilts, 8 2nd parity sows) using the AA deletion technique. A positive\u00a0control (PC) diet was formulated to contain all essential AA at 160% of current\u00a0recommendations (NRC 1998). Lysine, threonine, tryptophan and branchedchain\u00a0AA were each removed from the PC diet to 60% [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18120,19],"tags":[1809,102,105,23138,14,104,4591],"class_list":["post-14938","post","type-post","status-publish","format-standard","hentry","category-ontario-pork","category-pork-insight-articles","tag-acid","tag-gestation","tag-gilt","tag-lux","tag-pig","tag-sow","tag-tryptophan"],"_links":{"self":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/14938","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=14938"}],"version-history":[{"count":1,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/14938\/revisions"}],"predecessor-version":[{"id":14940,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/14938\/revisions\/14940"}],"wp:attachment":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=14938"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=14938"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=14938"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}