This study was conducted to determine the effect weaning has on intestinal alkaline<\/p>\n
phosphatase (IAP) activity. IAP is important for enteric health of the growing pig, playing roles<\/p>\n
in immune health, intestinal health, digestion, and fat absorption. 12 piglets were weaned at ten<\/p>\n
days old and put on standard commercial weaning diet and 12 piglets remained suckling with the<\/p>\n
sow as the control treatment. Overall, weaning decreased IAP affinity by 26% and maximal enzyme<\/p>\n
activity by 22%.\u00a0 The main effect was seen in the jejunal region becasue the jejunum expresses 84-86%<\/p>\n
of the total gut mucosal IAP activity. Weaning decreased the amount of IAP associated with the<\/p>\n
proximal jejunal apical membrane by 64% and proximal jejunal IAP mRNA by 58% which was<\/p>\n
associated with a decrease in the abundances of cytoplasmic (27%) and nuclear (29%) IAP caudal-<\/p>\n
associated homeobox transcription factor 1. In conclusion, weaning decreased the amount of<\/p>\n
IAP available in the pigs gut to facilitate gut and immune health. This may, in part, contribute<\/p>\n
to the growth check and increased susceptibility to gastro-intestinal disease in early weaned pigs.<\/p>\n","protected":false},"excerpt":{"rendered":"
This study was conducted to determine the effect weaning has on intestinal alkaline phosphatase (IAP) activity. IAP is important for enteric health of the growing pig, playing roles in immune health, intestinal health, digestion, and fat absorption. 12 piglets were weaned at ten days old and put on standard commercial weaning diet and 12 piglets […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18120,19],"tags":[2851,14,104,18011],"class_list":["post-14968","post","type-post","status-publish","format-standard","hentry","category-ontario-pork","category-pork-insight-articles","tag-fat","tag-pig","tag-sow","tag-tot"],"_links":{"self":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/14968","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/comments?post=14968"}],"version-history":[{"count":2,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/14968\/revisions"}],"predecessor-version":[{"id":14971,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/posts\/14968\/revisions\/14971"}],"wp:attachment":[{"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/media?parent=14968"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/categories?post=14968"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prairieswine.com\/rsc\/wp-json\/wp\/v2\/tags?post=14968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}