Three experiments conducted with weanling pigs evaluated the effects of vitamin E added to the drinking water or diet on plasma and tissue ƒ¿-tocopherol concentrations. It was found that when vitamin E was not added to the diet or water, plasma ƒ¿-tocopherol declined over the 21-d period. Although there were some interactions (P < 0.01), tissue and plasma ƒ¿-tocopherol concentrations increased linearly when vitamin E was added to the diet or water. The results from the second experiment indicate that plasma ƒ¿-tocopherol concentrations increased (P < 0.01) as vitamin E increased, with greater tissue ƒ¿-tocopherol concentrations (P < 0.01) when natural vitamin E was provided. The conclusions from experiment three plasma ƒ¿-tocopherol increased quadratically (P < 0.01) and plateaued at 8 to 10 h for each treatment group. These results indicate that adding vitaminEto the pigfs water supply at weaning was more effective in increasing plasma ƒ¿-tocopherol than when it was added to the diet during the initial 14 d postweaning, and that natural vitamin E was a superior source compared with synthetic vitamin E.