The present study was conducted to determine the effect of lipopolysaccharide (LPS)-induced immune challenge on performance and whole-body protein turnover in weanling pigs. It was found that the determination of protein turnover in weanling pigs would be useful in defining the effects of metabolic modifiers on protein accretion and refining protein requirements for growing animals. It has been already reported that immune stress alters nutrient requirements
(Williams et al., 1997). This study imply that regulating feed intake and providing sufficient amino acids for acute protein synthesis might be the nutritional strategies to alleviate the potential impacts of stress on animal health and production. But more researches are needed to quantify nutrient requirements for animals under stress.