The Take Care—Use Antibiotics Responsibly program is an industry initiative to address antibiotic use in pork production. The program has the potential to impact the ways in which antibiotics are used in US pork production. Success of the program will be dependent on the effectiveness of delivery channels of the program to the approximately 70,000 pork producers in the US. Because the program is not a certification or assessment program it will be hard to assess industry compliance with the principles and guidelines. The program does, however, demonstrate the industry’s good faith effort to address concerns about antibiotic use. Information about the program has been delivered to public health and regulatory audiences to emphasize the industry’s efforts. The program has been endorsed by producers supplying over 45% of the hogs marketed in the United States as well as by the American Association of Swine Veterinarians.